Journal of Zhejiang University

2022 IF (JZUS-A 3.2) (JZUS-B 5.1) (FITEE 3.0) (BDM 7.9)

Notice

more >

JZUS-B Call for Papers: Special issue on "Autism: From Bench to Bedside"
FITEE Special Feature on Computing and Network Convergence: Architecture, Theory, and Practice
FITEE Call for Papers: Special Feature on Intelligent Dynamics Optimization Methods and Their Applications
JZUS-B Call for Papers: Special issue on Molecular Nutrition and Chronic diseases
JZUS-B Call for Papers: Special Column on Gene Editing in Plant/Crop Science

Highlights

Journal of Zhejiang University-SCIENCE A (Applied Physics & Engineering) more >

1 of 5

Article
Stress relaxation properties of calcium silicate hydrate: a molecular dynamics study: The time-dependent viscoelastic response of cement-based materials to applied deformation is far from fully understood at the atomic level. Calcium silicate hydrate (C-S-H), the main hydration product of Portland cement, is responsible for the viscoelastic mechanism of cement-based materials. In this study, a molecular model of C-S-H was developed to explain the stress relaxation characteristics of C-S-H at different initial deformation states, Ca/Si ratios, temperatures, and water contents, which cannot be accessed experimentally. The stress relaxation of C-S-H occurs regardless of whether it is subjected to initial shear, tensile, or compressive deformation, and shows a heterogeneous chara...
DOI:10.1631/jzus.A2300476 Downloaded:1203 Clicked:2436 Cited:0 Comments:0 <Full Text>1203 <PPT>513
+Chinese Summary 水化矽酸鈣應力松弛特性的分(fēn)子動力學研究<595>水化矽酸鈣應力松弛特性的分(fēn)子動力學研究
作者：耿志(zhì)成¹，湯盛文^1,2，汪洋¹，阿胡寶¹，何真¹，吳凱²，王磊³
機構：¹武漢大(dà)學，水資(zī)源工(gōng)程與調度全國重點實驗室，中(zhōng)國武漢，430072；²同濟大(dà)學，先進土木工(gōng)程材料教育部重點實驗室，中(zhōng)國上海，200092；³西安建築科技大(dà)學，材料科學與工(gōng)程學院，中(zhōng)國西安，710055
目的：水化矽酸鈣（C-S-H）是波特蘭水泥的主要水化産物(wù)，是影響水泥基材料粘彈性機制的主要成分(fēn)之一(yī)。然而，人們還未能在原子層面上完全理解水泥基材料在外(wài)加變形作用下(xià)随時間變化的粘彈性響應。本文旨在通過建立不同鈣矽比的C-S-H模型，以分(fēn)子動力學模拟的方式系統研究不同因素對水化矽酸鈣應力松弛性能的影響。
創新點：1.基于分(fēn)子動力學模拟，獲得C-S-H的應力松弛特性；2.研究應變狀态、鈣矽比和内部水含量對C-S-H應力松弛的影響，揭示其在應力松弛過程中(zhōng)所涉及的内部結構及能量變化。
方法：1.通過各原子基團的均方位移在應力松弛過程中(zhōng)考慮C-S-H層間區域的粘度變化；2.基于時間相關函數，在不同應變狀态、鈣矽比以及溫度的條件下(xià)研究C-S-H層間區域涉及到的化學鍵斷裂與重組；3.闡明氫鍵網絡和C-S-H形态對不同含水量下(xià)C-S-H應力松弛特性演變的影響。
結論：1.在不同的初始變形條件下(xià)，C-S-H應力松弛響應均會發生(shēng)，并顯示出非均質特征；2.鈣矽比的增大(dà)以及溫度的提高會導緻水分(fēn)子、羟基和層間鈣原子的運動加快，從而引起C-S-H層間區域的粘度降低，進而導緻C-S-H的初始應力及殘餘應力降低；3.由于水分(fēn)子會影響C-S-H的形貌以及層間氫鍵網絡，所以C-S-H在不同水含量時展現出不同的應力松弛特性。

關鍵詞組：水化矽酸鈣；應力松弛；鈣矽比；溫度；水含量；原子模拟
Review
Inkjet 3D bioprinting for tissue engineering and pharmaceutics: 3D bioprinting has the capability to create 3D cellular constructs with the desired shape using a layer-by-layer approach. Inkjet 3D bioprinting, as a key component of 3D bioprinting, relies on the deposition of cell-laden droplets to create native-like tissues/organs which are envisioned to be transplantable into human body for replacing damaged ones. Benefiting from its superiorities such as high printing resolution and deposition accuracy, inkjet 3D bioprinting has been widely applied to various areas, including, but not limited to, tissue engineering and drug screening in pharmaceutics. Even though inkjet 3D bioprinting has proved its feasibility and versatility in various fields, the cu...
DOI:10.1631/jzus.A2200569 Downloaded:2306 Clicked:30118 Cited:0 Comments:0 <Full Text>2306 <PPT>1606
+Chinese Summary 噴墨生(shēng)物(wù)3D打印的組織工(gōng)程和藥學應用<2909>噴墨生(shēng)物(wù)3D打印的組織工(gōng)程和藥學應用
作者：趙登科^1,2,3，徐赫崎^1,3，尹俊^1,2，楊華勇¹
機構：¹浙江大(dà)學，流體(tǐ)動力與機電系統國家重點實驗室，中(zhōng)國杭州，310058；²浙江大(dà)學，浙江省三維打印工(gōng)藝與裝備重點實驗室，中(zhōng)國杭州，310058；³這些作者對本文的貢獻相同
概要：生(shēng)物(wù)3D打印具有通過層層疊加增材制造的方式構建所需載活細胞3D結構的能力。作爲生(shēng)物(wù)3D打印技術的重要組成部分(fēn)，噴墨生(shēng)物(wù)3D打印利用載細胞液滴作爲基本單元，構造仿生(shēng)組織或器官，以期用于替代人體(tǐ)損傷或病變的組織或器官。由于其優異的打印精度和準确性，噴墨生(shēng)物(wù)3D打印目前已被廣泛應用于組織工(gōng)程和藥物(wù)研發等領域。然而，盡管大(dà)量的應用已證明其在不同領域内的可行性和廣泛适用性，噴墨生(shēng)物(wù)3D打印仍然受限于生(shēng)物(wù)材料的選擇和打印工(gōng)藝。本文針對噴墨生(shēng)物(wù)3D打印，首先歸納總結了現有關鍵打印技術、可打印生(shēng)物(wù)材料和其在組織工(gōng)程和藥學領域内的典型應用，進而對其面臨的關鍵挑戰和潛在解決方案進行讨論。

關鍵詞組：噴墨生(shēng)物(wù)3D打印；生(shēng)物(wù)材料；體(tǐ)外(wài)組織模型；體(tǐ)内組織替代物(wù)；藥物(wù)篩選
Review
Development of amphibious biomimetic robots: Amphibious robots are becoming increasingly important for civilian, scientific, and environmental missions. They are widely used in disaster rescue, ecosystem monitoring, and entertainment. However, some have two different locomotion systems that need to be changed manually to fulfill both swimming in the water and moving on land, which may reduce their efficiency and reliability. Applying bioinspiration and biomimetics, many recently developed amphibious robots can undertake various tasks in complex amphibious environments with high mobility, flexibility, and energy efficiency. This review overviews the latest developments in amphibious robots, emphasizing biomimetic design concepts, backbo...
DOI:10.1631/jzus.A2100137 Downloaded:3466 Clicked:16959 Cited:0 Comments:0 <Full Text>3466 <PPT>1698
+Chinese Summary 水陸兩栖仿生(shēng)機器人的發展與展望<2880>水陸兩栖仿生(shēng)機器人的發展與展望
作者：白(bái)向娟，尚建忠，羅自榮，蔣濤，殷謙
機構：國防科技大(dà)學，智能科學學院，智能機械與儀器系，中(zhōng)國長沙，410073
目的：1.通過對仿生(shēng)生(shēng)物(wù)行進功能和結構特性等特征的研究，分(fēn)析總結現有兩栖仿生(shēng)機器人的特征。2.分(fēn)析總結探讨仿生(shēng)生(shēng)物(wù)的自身生(shēng)物(wù)結構優勢，并通過應用仿生(shēng)學提高水陸兩栖環境下(xià)的機器人性能。
創新點：1.從13種不同仿生(shēng)原型的角度歸納了典型的兩栖機器人，比較了目前兩栖機器人的研究技術參數，并總結了兩栖機器人10種不同的推進方法以及行駛速度、工(gōng)作效率、機動性和穩定性。2.創新性地提出了兩栖機器人運動能力評價指标和仿生(shēng)機器人仿生(shēng)化程度評價方法。
方法：1.通過查閱現有多種水陸兩栖仿生(shēng)機器人的研究技術參數，總結兩栖機器人的功能和結構等特性。2.通過應用性驗證，對提出的仿生(shēng)機器人性能進行評價比較分(fēn)析。
結論：1.應用仿生(shēng)學的設計理念，可以有效地提高水陸兩栖仿生(shēng)機器人在複雜(zá)兩栖環境中(zhōng)的機動性、靈活性和能效等性能。2.通過比較分(fēn)析現有兩栖機器人的推進方式、工(gōng)作效率和機動性等性能，可以将該仿生(shēng)學設計方法和機理應用到其他種類的機器人研究中(zhōng)，從而提高機器人在民用、科學和環境任務中(zhōng)的應用潛能。

關鍵詞組：水陸兩栖機器人；仿生(shēng)機器人；仿生(shēng)技術；智能機器人；機器人學
Review
Development of electric construction machinery in China: a review of key technologies and future directions: The issues of energy shortage and environmental pollution have accelerated the electrification of construction machinery (CM) industry globally. In China, the amount of electric construction machinery (ECM) has been growing across the industry. The sales of ECM are estimated to reach 600 000 vehicles by the end of 2025, while the total demand for battery power will reach 60 GWh. However, the development of ECM still faces critical challenges including reliable power supply and energy distribution among various components. In this review, we primarily focus on important technological breakthroughs and the difficulties faced by the CM industry in China. An overview of ECM including classificat...
DOI:10.1631/jzus.A2100006 Downloaded:10287 Clicked:15950 Cited:0 Comments:0 <Full Text>10287 <PPT>5159
+Chinese Summary 中(zhōng)國工(gōng)程機械電氣化發展的關鍵技術綜述<2612>中(zhōng)國工(gōng)程機械電氣化發展的關鍵技術綜述概要:能源短缺和環境污染問題加速了全球工(gōng)程機械行業的電氣化進程.在中(zhōng)國,整個行業内的電動工(gōng)程機械數量一(yī)直在快速增長.在未來5年内,電動工(gōng)程機械的銷量預計達到六十萬輛,對電池的整體(tǐ)需求将達到60 GWh.然而,工(gōng)程機械電氣化發展仍然面臨着嚴峻挑戰,其中(zhōng)包括可靠的電力供應和組件間能源分(fēn)配問題.本文主要讨論了中(zhōng)國工(gōng)程機械産業中(zhōng)的重大(dà)技術突破和面臨的挑戰.首先概述了電動工(gōng)程機械的分(fēn)類及其特點.其次,讨論了純電驅動系統中(zhōng)電動機、儲能單元等關鍵部件的選型及控制策略.詳細分(fēn)析了混合動力驅動系統的結構設計和動力匹配等技術特性.電池管理系統(BMS)對于确保電池處于适當的健康狀态并提供穩定的能源具有十分(fēn)重要的意義.在這裏,我(wǒ)們廣泛地總結了電池管理系統的發展進程.此外(wài),我(wǒ)們大(dà)緻估算了中(zhōng)國工(gōng)程機械的總排放(fàng)量以及采用電動工(gōng)程機械所帶來的潛在的環境效益.最後,闡述了電動工(gōng)程機械的未來研究方向和産業化發展前景.關鍵詞組：工(gōng)程機械;電力驅動系統;電池管理系統;能量回收;電氣化
Review
Internal flow structure, fault detection, and performance optimization of centrifugal pumps: This review mainly summarizes the latest developments in the internal flow field and external characteristics of centrifugal pumps. In particular, the latest findings of centrifugal pumps focused on turbulence and cavitation models, flow visualization methods, and fault detection based on noise and vibration. The external characteristics, cavitation, and vibration of the centrifugal pump were extensively discussed. In addition, advanced multi-objective optimization methods for improving impeller’s efficiency and reducing net positive suction head (NPSH) were briefed. Although some progress was made in this field, there remain many unsolved problems, such as monitoring and modeling of ...
DOI:10.1631/jzus.A1900608 Downloaded:7018 Clicked:31340 Cited:0 Comments:0 <Full Text>7018 <PPT>5739
+Chinese Summary 離(lí)心泵内部流動結構、性能優化與故障檢測綜述<3430>離(lí)心泵内部流動結構、性能優化與故障檢測綜述目的:對離(lí)心泵的内部流動機理和外(wài)部特性、振動監測和性能優化進行研究,并對新興研究趨勢進行評述,爲提高離(lí)心泵系統的能效提供參考建議.
創新點:1. 探讨了最新的用于離(lí)心泵數值模拟的湍流模型和空化模型的研究成果以及利用可視化方法揭示離(lí)心泵内部複雜(zá)流動現象的最新進展. 2. 對離(lí)心泵的外(wài)部特性、空化和振動進行了廣泛的讨論,并總結出一(yī)種提高離(lí)心泵在工(gōng)程應用中(zhōng)的效率和揚程、降低汽蝕餘量的适用性強的離(lí)心泵葉輪多目标優化方法.
方法:1. 對離(lí)心泵的内部流動機理進行綜述,以充分(fēn)了解離(lí)心泵内部複雜(zá)的流場結構和能量損失機理. 2. 對離(lí)心泵外(wài)部特性進行研究,解釋内部非定常流動與外(wài)部特性的耦合關系. 3. 介紹與離(lí)心泵在運行過程中(zhōng)壓力脈動的監測和測量相關的最新研究進展. 4. 詳細介紹優化離(lí)心泵性能的各種方法和措施.
結論:1. 盡管對離(lí)心泵内部流動現象機理及流場結構的研究已經取得了一(yī)定進展,但研究中(zhōng)仍存在一(yī)些亟待解決的問題,如初生(shēng)空化的監測與預防、泵内旋轉失速現象發生(shēng)發展的規律、數值模拟和實驗之間不可忽視的數據差異等. 2. 針對這些問題,開(kāi)發高精度的計算流體(tǐ)動力學仿真模型,結合關鍵過流部件的優化設計來減少流動不穩定性和提高性能,以及運用現代流動顯示技術的最新設備進行大(dà)量的仔細繁雜(zá)的試驗與測量工(gōng)作,是非常必要和重要的,也是未來泵内流動研究的趨勢.關鍵詞組：離(lí)心泵; 氣液兩相流; 空化機理; 壓力脈動; 多目标優化

Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology) more >

1 of 5

Review
Overview of the main biological mechanisms linked to changes in periodontal ligament stem cells and the inflammatory microenvironment: Periodontitis is a complex chronic inflammatory disease. The invasion of pathogens induces the inflammatory microenvironment in periodontitis. Cell behavior changes in response to changes in the microenvironment, which in turn alters the local inflammatory microenvironment of the periodontium through factors secreted by cells. It has been confirmed that periodontal ligament stem cells (PDLSCs) are vital in the development of periodontal disease. Moreover, PDLSCs are the most effective cell type to be used for periodontium regeneration. This review focuses on changes in PDLSCs, their basic biological behavior, osteogenic differentiation, and drug effects caused by the inflammatory microenviro...
DOI:10.1631/jzus.B2200576 Downloaded:1424 Clicked:2707 Cited:0 Comments:0 <Full Text>1424 <PPT>825
+Chinese Summary 牙周膜幹細胞與炎症微環境相互作用的主要生(shēng)物(wù)學機制概述<856>牙周膜幹細胞與炎症微環境相互作用的主要生(shēng)物(wù)學機制概述
趙雪濤¹，林泓兵¹，丁瞳¹，王亞玮¹，柳娜²，申玉芹¹
¹吉林大(dà)學口腔醫院牙周科，吉林省牙發育及颌骨重塑與再生(shēng)重點實驗室，中(zhōng)國長春市，130021
²廣州醫科大(dà)學附屬口腔醫院牙周科，廣州市口腔再生(shēng)醫學基礎與應用研究重點實驗室，中(zhōng)國廣州市，510182
概要：牙周炎是一(yī)種複雜(zá)的慢(màn)性炎症性疾病，在此過程中(zhōng)病原體(tǐ)的入侵導緻了炎症微環境的發生(shēng)。細胞的生(shēng)物(wù)學性質在炎症微環境的作用下(xià)發生(shēng)改變，同時又(yòu)可以通過分(fēn)泌細胞因子對牙周組織的炎症微環境進行調節。研究證明，牙周膜幹細胞在牙周疾病過程中(zhōng)至關重要。此外(wài)，牙周膜幹細胞被證明是在牙周組織再生(shēng)過程中(zhōng)最有效的幹細胞類型。本綜述關注在炎症微環境影響下(xià)，牙周膜幹細胞生(shēng)物(wù)學性質、成骨分(fēn)化能力以及藥物(wù)對細胞的影響等方面，有利于進一(yī)步理解上述因素對牙周組織穩态的影響。另外(wài)，我(wǒ)們還對牙周膜幹細胞影響炎症微環境的相關機制進行了讨論。

關鍵詞組：炎症微環境；炎症調節；成骨分(fēn)化；牙周膜幹細胞；牙周炎
Review
Seasonal coronaviruses and SARS-CoV-2: effects of preexisting immunity during the COVID-19 pandemic: Although the coronavirus disease 2019 (COVID-19) epidemic is still ongoing, vaccination rates are rising slowly and related treatments and drugs are being developed. At the same time, there is increasing evidence of preexisting immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in humans, mainly consisting of preexisting antibodies and immune cells (including T cells and B cells). The presence of these antibodies is mainly due to the seasonal prevalence of four common coronavirus types, especially OC43 and HKU1. The accumulated relevant evidence has suggested that the target of antibodies is mainly the S2 subunit of S protein, followed by evolutionary conservative ...
DOI:10.1631/jzus.B2200049 Downloaded:1902 Clicked:3290 Cited:0 Comments:0 <Full Text>1902 <PPT>1532
+Chinese Summary 季節性冠狀病毒和SARS-CoV-2：在COVID-19疫情中(zhōng)預存免疫的影響<2163>季節性冠狀病毒和SARS-CoV-2：在COVID-19疫情中(zhōng)預存免疫的影響
王剛¹，向澤²，汪偉³，陳智¹
¹浙江大(dà)學醫學院附屬第一(yī)醫院傳染病診治國家重點實驗室、國家感染性疾病臨床醫學研究中(zhōng)心、國家傳染病醫學中(zhōng)心、感染性疾病診治協同創新中(zhōng)心，中(zhōng)國杭州市，310003
²浙江大(dà)學醫學院，中(zhōng)國杭州市，310003
³江蘇省寄生(shēng)蟲病研究所，中(zhōng)國無錫市，214064
摘要：新型冠狀病毒肺炎（COVID-19）疫情仍在持續，疫苗接種率正在緩慢(màn)上升，相關治療方法和藥物(wù)也在研發中(zhōng)。越來越多的證據表明，人類群體(tǐ)中(zhōng)已存在針對嚴重急性呼吸綜合征冠狀病毒2型（SARS-CoV-2）的免疫力，包括抗體(tǐ)和免疫細胞（T細胞和B細胞）。這些抗體(tǐ)的存在主要是由于四種常見冠狀病毒類型（尤其OC43和HKU1）的季節性流行所緻。預存抗體(tǐ)的靶點主要是S蛋白(bái)的S2亞基，其次是核衣殼（N）等蛋白(bái)進化保守區。此外(wài)，人群中(zhōng)也存在預存的記憶T細胞和B細胞。預存抗體(tǐ)可以幫助身體(tǐ)抵禦SARS-CoV-2感染，降低COVID-19的嚴重程度并迅速增加感染後的免疫反應。這些多重影響可以直接影響某些個體(tǐ)的疾病進展，甚至死亡的風險性。除了積極作用外(wài)，預存免疫也可能産生(shēng)消極後果，例如抗體(tǐ)依賴性增強（ADE）和原始抗原原罪（OAS），其流行程度需要進一(yī)步确定。未來，更多的研究應側重于評估已有免疫力在COVID-19中(zhōng)的作用，采取适當的政策和策略來抗擊新冠大(dà)流行，同時也要考慮已有免疫力的疫苗開(kāi)發。

關鍵詞組：嚴重急性呼吸綜合征冠狀病毒2型（SARS-CoV-2）；新型冠狀病毒肺炎（COVID-19）；預存免疫；季節性冠狀病毒；疫苗
Review
Emerging role of protein modification in inflammatory bowel disease: The onset of inflammatory bowel disease (IBD) involves many factors, including environmental parameters, microorganisms, and the immune system. Although research on IBD continues to expand, the specific pathogenesis mechanism is still unclear. Protein modification refers to chemical modification after protein biosynthesis, also known as post-translational modification (PTM), which causes changes in the properties and functions of proteins. Since proteins can be modified in different ways, such as acetylation, methylation, and phosphorylation, the functions of proteins in different modified states will also be different. Transitions between different states of protein or changes in modificati...
DOI:10.1631/jzus.B2100114 Downloaded:3208 Clicked:4323 Cited:0 Comments:0 <Full Text>3208 <PPT>1701
+Chinese Summary 蛋白(bái)質修飾在炎症性腸病中(zhōng)作用研究進展<1969>蛋白(bái)質修飾在炎症性腸病中(zhōng)作用研究進展
摘要：炎症性腸病（inflammatory bowel disease，IBD）的發病涉及許多因素，包括環境、微生(shēng)物(wù)和免疫系統的改變。盡管對IBD的研究不斷深入，但具體(tǐ)的發病機制尚不清楚。蛋白(bái)質修飾是指蛋白(bái)質生(shēng)物(wù)合成後的化學修飾，也稱爲翻譯後修飾（post-translational modification，PTM），使蛋白(bái)質的性質和功能發生(shēng)變化。由于蛋白(bái)質可以通過乙酰化、甲基化和磷酸化等不同方式進行修飾，因此不同修飾狀态的蛋白(bái)質的功能也會有所不同。蛋白(bái)質不同狀态之間的轉換或修飾位點的變化可以調節蛋白(bái)質的特性和功能，如NEDD8蛋白(bái)修飾、SUMO化修飾、糖基化和乙酰化等修飾可以通過改變腸道菌群、調節免疫細胞、調節細胞因子（如IL-1β、TNF-α、IFN-γ），最終維持腸上皮屏障的穩定性。在這篇綜述中(zhōng)，我(wǒ)們關注當前對PTM的理解，并描述其在IBD發病機制中(zhōng)的調節作用。

關鍵詞組：炎症性腸病（IBD）；蛋白(bái)質修飾；NEDD8蛋白(bái)修飾；SUMO化修飾；糖基化；乙酰化
Review
Application of extracorporeal therapies in critically ill COVID-19 patients: The coronavirus disease 2019 (COVID-19) pandemic is a major public health event caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 has spread widely all over the world. A high proportion of patients become severely or critically ill, and suffer high mortality due to respiratory failure and multiple organ dysfunction. Therefore, providing timely and effective treatment for critically ill patients is essential to reduce overall mortality. Convalescent plasma therapy and pharmacological treatments, such as aerosol inhalation of interferon-α (IFN-α), corticosteroids, and tocilizumab, have all been applied in clinical practice; however, their effects rema...
DOI:10.1631/jzus.B2100344 Downloaded:4615 Clicked:7725 Cited:0 Comments:0 <Full Text>4615 <PPT>4225
+Chinese Summary 體(tǐ)外(wài)療法在重症COVID-19患者中(zhōng)的應用<2112>體(tǐ)外(wài)療法在重症COVID-19患者中(zhōng)的應用
概要：新型冠狀病毒型肺炎（COVID-19）大(dà)流行是由嚴重急性呼吸系統綜合症冠狀病毒2（SARS-CoV-2）引起的重大(dà)公共衛生(shēng)事件。COVID-19已在世界各地廣泛傳播。很大(dà)比例的患者因呼吸衰竭和多器官功能障礙而發展爲重症或危重症，并且死亡率很高。因此，爲危重患者提供及時有效的治療對于降低總體(tǐ)死亡率至關重要。恢複期血漿治療，幹擾素-α（IFN-α）、皮質類固醇和托珠單抗的氣霧吸入等藥物(wù)治療均已應用于臨床治療，但其效果仍存在争議。最近的研究表明，體(tǐ)外(wài)療法可能在治療COVID-19危重患者方面發揮潛在作用。在這篇綜述中(zhōng)，我(wǒ)們闡述了連續性腎髒替代療法（CRRT）、治療性血漿置換（TPE）、血液吸附（HA）、體(tǐ)外(wài)膜肺氧合（ECMO）和體(tǐ)外(wài)二氧化碳清除（ECCO₂R）在重症COVID-19患者中(zhōng)的應用，爲COVID-19的進一(yī)步診斷和治療提供支持。

關鍵詞組：新型冠狀病毒型肺炎（COVID-19）；重症疾病；細胞因子釋放(fàng)綜合征（CRS）；急性腎損傷（AKI）；體(tǐ)外(wài)療法
Review
Research advances in bioactive components and health benefits of jujube (Ziziphus jujuba Mill.) fruit: Jujube (Ziziphus jujuba Mill.), a highly nutritious and functional fruit, is reported to have various health benefits and has been extensively planted worldwide, especially in China. Many studies have shown that bioactive components derived from jujube fruit have significant nutritional and potential biological effects. In this paper, the latest progress in research on major bioactive compounds obtained from jujube is reviewed, and the potential biological functions of jujube fruit resources are discussed. As a dietary supplement, jujube fruit is well recognized as a healthy food which contains a variety of bioactive substances, such as polysaccharides, polyphenols, amino acids, nucle...
DOI:10.1631/jzus.B2000594 Downloaded:6197 Clicked:11527 Cited:0 Comments:0 <Full Text>6197 <PPT>4805
+Chinese Summary 紅棗生(shēng)物(wù)活性成分(fēn)及其保健作用的研究進展<1858>紅棗生(shēng)物(wù)活性成分(fēn)及其保健作用的研究進展
摘要：紅棗作爲一(yī)種膳食補充劑，是公認的健康食品。它含有多種生(shēng)物(wù)活性物(wù)質，如多糖、多酚、氨基酸、核苷酸、脂肪酸和維生(shēng)素等。這些活性物(wù)質具有抗癌、抗氧化、抗炎、降血脂、降血糖、免疫調節、神經保護、鎮靜和抗病毒等生(shēng)理功能。除此之外(wài)，本文還歸納了紅棗果實中(zhōng)的生(shēng)物(wù)堿和膳食纖維及其生(shēng)理功能。同時，對影響棗樹(shù)果實資(zī)源開(kāi)發利用的相關問題進行了探讨，并提出了未來紅棗營養功能的研究方向。本文将爲紅棗産品的開(kāi)發及紅棗營養成分(fēn)在功能性食品中(zhōng)的應用提供一(yī)定的參考依據。

關鍵詞組：紅棗；功能成分(fēn)；生(shēng)物(wù)活性；功能食品；保健作用

Frontiers of Information Technology & Electronic Engineering (since 2015)
more >

1 of 5

Former title: Journal of Zhejiang University-SCIENCE C (Computers & Electronics)

Review
Big data storage technologies: a survey: There is a great thrust in industry toward the development of more feasible and viable tools for storing fast-growing volume, velocity, and diversity of data, termed ‘big data’. The structural shift of the storage mechanism from traditional data management systems to NoSQL technology is due to the intention of fulfilling big data storage requirements. However, the available big data storage technologies are inefficient to provide consistent, scalable, and available solutions for continuously growing heterogeneous data. Storage is the preliminary process of big data analytics for real-world applications such as scientific experiments, healthcare, social networks, and e-business....
DOI:10.1631/FITEE.1500441 Downloaded:13822 Clicked:24145 Cited:0 Comments:0 <Full Text>13822 <PPT>8495
+Chinese Summary 大(dà)數據存儲技術綜述<3031>大(dà)數據存儲技術綜述
概要：對于容量快速增長、日趨多元化的大(dà)數據，業界亟需開(kāi)發可行性更好的存儲工(gōng)具。爲滿足大(dà)數據存儲需求，存儲機制已經形成從傳統數據管理系統到NoSQL技術的結構化轉移。然而，目前可用的大(dà)數據存儲技術無法爲持續增長的異構數據提供一(yī)緻、可擴展和可用的解決方案。在科學實驗、醫療保健、社交網絡和電子商(shāng)務等實際應用中(zhōng)，存儲是大(dà)數據分(fēn)析的第一(yī)步。截至目前，亞馬遜、谷歌和阿帕奇等公司形成了大(dà)數據存儲方案的行業标準，但尚未有關于大(dà)數據存儲技術性能和容量提升的深入調查和文獻報告。本文旨在對目前可用于大(dà)數據的最先進的存儲技術進行全面調查，提供了一(yī)個明确的大(dà)數據存儲技術分(fēn)類方法，以幫助數據分(fēn)析師和研究人員(yuán)了解和選擇更适合其需求的存儲機制。我(wǒ)們使用布魯爾的CAP定理比較和分(fēn)析了現有存儲方法，評估了不同存儲架構的性能，讨論了存儲技術的意義、應用及其對其他類别數據的支持。爲了加快部署可靠和可擴展的存儲系統，文中(zhōng)還突出了未來研究面臨的幾個挑戰。

關鍵詞組：大(dà)數據；大(dà)數據存儲；NoSQL數據庫；分(fēn)布式數據庫；CAP定理；可擴展性；一(yī)緻性-分(fēn)區彈性；可用性-分(fēn)區彈性
Article
Sparse fast Clifford Fourier transform: The Clifford Fourier transform (CFT) can be applied to both vector and scalar fields. However, due to problems with big data, CFT is not efficient, because the algorithm is calculated in each semaphore. The sparse fast Fourier transform (sFFT) theory deals with the big data problem by using input data selectively. This has inspired us to create a new algorithm called sparse fast CFT (SFCFT), which can greatly improve the computing performance in scalar and vector fields. The experiments are implemented using the scalar field and grayscale and color images, and the results are compared with those using FFT, CFT, and sFFT. The results demonstrate that SFCFT can effectively improve the performa...
DOI:10.1631/FITEE.1500452 Downloaded:8422 Clicked:18621 Cited:0 Comments:0 <Full Text>8422 <PPT>8311
+Chinese Summary 稀疏快速Clifford傅裏葉變換<1037>稀疏快速Clifford傅裏葉變換
概要：Clifford傅裏葉變換（Clifford Fourier transform, CFT）可以應用于矢量場和标量場，但無法有效解決大(dà)數據問題，因爲該算法是基于每個信号量計算的。稀疏快速傅裏葉變換（sparse fast Fourier transform, sFFT）理論通過選擇性地使用輸入數據來處理大(dà)數據問題。受之啓發，我(wǒ)們提出一(yī)個稱爲稀疏快速Clifford傅裏葉變換（sparse fast CFT, SFCFT）的算法，該算法能夠大(dà)幅度提高在标量場和矢量場中(zhōng)的計算性能。實驗對标量場、灰度圖和彩色圖像數據進行處理，通過與FFT，CFT和sFFT進行比較，表明SFCFT可以有效提升多矢量信号處理的性能。

關鍵詞組：稀疏快速傅裏葉變換（sFFT）；Clifford傅裏葉變換（CFT）；稀疏快速Clifford傅裏葉變換（SFCFT）；Clifford代數
Article
Simulation model of self-organizing pedestrian movement considering following behavior: A new force is introduced in the social force model (SFM) for computing following behavior in pedestrian counterflow, whereby an individual tries to approach others in the same direction to avoid conflicts with pedestrians from the opposite direction. The force, like a kind of gravitation, is modeled based on the movement state and visual field of the pedestrian, and is added to the classical SFM. The modified model is presented to study the impact of following behavior on the process of lane formation, the conflict, the number of lanes formed, and the traffic efficiency in the simulations. Simulation results show that the following behavior has a significant effect on the phenomenon of lane...
DOI:10.1631/FITEE.1601592 Downloaded:9188 Clicked:18204 Cited:0 Comments:0 <Full Text>9188 <PPT>8476
+Chinese Summary 考慮跟随行爲的行人自組織運動仿真模型<1289>考慮跟随行爲的行人自組織運動仿真模型
概要：在本文中(zhōng)一(yī)種新的力學模型被引入到社會力模型中(zhōng)，用來仿真相向行人流中(zhōng)的跟随行爲。這種跟随行爲指的是行人通過接近同向行人以避免與反向行人沖突的行爲。新的力學模型類似于一(yī)種引力模型，在建模過程中(zhōng)考慮了行人的視野範圍、自身的運動狀态、被跟随行人的運動狀态等因素。我(wǒ)們利用新的力學模型對相向行人流進行了仿真，研究了跟随行爲對渠化現象、行人間沖突以及雙向通道通行效率的影響。仿真結果表明：跟随行爲能促進渠化現象形成，并能起到緩解相向行人流擁堵的作用；跟随行爲具有降低相向行人流沖突次數的作用，這種作用在入口流量較低時并不明顯，但随着行人流量的升高而增強。跟随行爲能夠提高雙向通道的通行效率，并且跟随行爲的強度參數越大(dà)通道的通行效率越高。

關鍵詞組：引力模型；相向行人流；社會力模型；渠化現象；自組織行爲
Article
Flight control for air-breathing hypersonic vehicles using linear quadratic regulator design based on stochastic robustness analysis: The flight dynamics model of air-breathing hypersonic vehicles (AHVs) is highly nonlinear and multivariable coupling, and includes inertial uncertainties and external disturbances that require strong, robust, and high-accuracy controllers. In this paper, we propose a linear-quadratic regulator (LQR) design method based on stochastic robustness analysis for the longitudinal dynamics of AHVs. First, input/output feedback linearization is used to design LQRs. Second, subject to various system parameter uncertainties, system robustness is characterized by the probability of stability and desired performance. Then, the mapping relationship between system robustness and LQR parameters is establish...
DOI:10.1631/FITEE.1601363 Downloaded:8478 Clicked:17834 Cited:0 Comments:0 <Full Text>8478 <PPT>8362
+Chinese Summary 基于随機魯棒性分(fēn)析的吸氣式高超聲速飛行器線性二次調節器設計<1154>基于随機魯棒性分(fēn)析的吸氣式高超聲速飛行器線性二次調節器設計
概要：吸氣式高超聲速飛行器（air-breathing hypersonic vehicle, AHV）的飛行動力學模型具有高度非線性與多變量耦合等特性，且受到内部不确定性與外(wài)部幹擾的綜合影響，因此需要具有強魯棒性與高精度的控制器。本文介紹了一(yī)種改進的基于随機魯棒性分(fēn)析的線性二次調節器（linear-quadratic regulator, LQR）設計方法，用于AHV的縱向飛行控制器設計。首先，應用輸入輸出反饋線性化技術設計LQR控制器。其次，基于系統參數的不确定性，将系統魯棒性表征爲滿足穩定性與設計指标要求的概率，并構建系統魯棒性與LQR參數之間的映射關系。爲了實現系統魯棒性最大(dà)化的目标，提出一(yī)種全新的混合粒子群優化算法對LQR的控制參數進行尋優計算。在優化叠代的過程中(zhōng)，使用切諾夫邊界理論确定蒙特卡洛估計的随機樣本量。最後，仿真結果表明該優化算法可以高效地獲取滿足設計要求的LQR控制參數最優解。

關鍵詞組：吸氣式高超聲速飛行器；随機魯棒性分(fēn)析；二次線性調節器；粒子群優化；改進混合粒子群算法
Article
Steering control for underwater gliders: Steering control for an autonomous underwater glider (AUG) is very challenging due to its changing dynamic characteristics such as payload and shape. A good choice to solve this problem is online system identification via in-field trials to capture current dynamic characteristics for control law reconfiguration. Hence, an online polynomial estimator is designed to update the yaw dynamic model of the AUG, and an adaptive model predictive control (MPC) controller is used to calculate the optimal control command based on updated estimated parameters. The MPC controller uses a quadratic program (QP) to compute the optimal control command based on a user-defined cost function. The cost function h...
DOI:10.1631/FITEE.1601735 Downloaded:8192 Clicked:16489 Cited:0 Comments:0 <Full Text>8192 <PPT>8381
+Chinese Summary 水下(xià)滑翔機航向控制<1827>水下(xià)滑翔機航向控制
概要：水下(xià)滑翔機動力學特性随有效載荷及外(wài)形變化而變化，其航向控制富有挑戰性。解決方法是使用在線系統辨識算法捕捉當前動力學特性，更新運動模型。爲此，我(wǒ)們設計了一(yī)個在線多項式辨識器，不斷更新當前動力學模型，同時用一(yī)個自适應模型預測控制器計算并輸出最優化的控制指令。該控制器根據用戶自定義的指标函數，使用二次規劃方法得到最優控制指令。該指标函數由兩項組成，一(yī)項用來表達軌迹跟蹤性能，一(yī)項用來表達輸入指令抑制性能。輸入指令抑制性能一(yī)定程度上可以代表該控制器的能量消耗性能。設計師可以通過調節這兩項的權重，平衡兩個控制器的性能。比較二次與五次多項式模型的控制效果，發現：二次多項式模型不足以表達無人機的動力學特性，且控制結果易發生(shēng)劇烈波動。硬件在環模拟以及湖試結果驗證了控制器性能。

關鍵詞組：水下(xià)滑翔機；在線系統辨識；航向控制；自适應控制；最優控制；節能控制；硬件在環模拟