Why can tumor bite hard bones? ZJU researchers make a new discovery
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2024-05-09
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Bone is one of the most common sites of early metastasis of cancer and is also a "hotbed" for tumor cells. Why do tumor cells go after hard bones first? The latest study by teams from Prof. FAN Shunwu and Prof. LIN Xianfeng’s Lab from Sir Run Run Shaw Hospital (SRRSH), affiliated with Zhejiang University School of Medicine, found that they are directed at osteoclasts, the only cells in the human body that can secrete acid and dissolve bone. By feeding them closely, tumor cells "r...
FAHZU highlights the global influence of China’s innovations in CAR T-cell therapy
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2024-04-10
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In a significant stride for China's presence on the global stage of cell immunotherapy, Professor HUANG He from theBone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine (FAHZU) has been at the forefront, showcasing remarkable advancements in CAR T-cell therapy. Recently, the contributions of his team were highlighted in February, during the 6th European CAR-T Conference held in Valencia, Spain, where he delivered insig...
World's first application of CAR-T therapy for childhood-onset SLE
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2024-04-05
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Chimeric Antigen Receptor T-cell (CAR-T) therapy, a pioneering treatment for B-cell malignancies, has garnered significant attention lately due to its promising potential in tackling severe autoimmune disorders, especially systemic lupus erythematosus (SLE). Nonetheless, there is a notable absence of reported applications of CAR-T therapy in pediatric SLE patients.In March 2024, the Children's Hospital of Zhejiang University School of Medicine initiated the groundbreaking use of CAR-T t...
ZJU scientists unravel the enigma of fear defensive behavior
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2024-04-03
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On March 5, the research team led by Professors YU Yanqin, DUAN Shumin and YANG Hongbin from the Zhejiang University School of Brain Science and Brain Medicine published an open-access article titled “Control of defensive behavior by the nucleus of Darkschewitsch GABAergic neurons” in the journal National Science Review. This groundbreaking work reveals, for the first time, the crucial role of GABAergic neurons in the nucleus of Darkschewitsch (ND) in modulating defensive behavior, t...
Freeze-dried fruits inspire innovation in cancer therapy
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2024-03-21
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Freeze-drying technique, commonly used for preparation of snacks from fruits and vegetables, is now utilized for generating therapeutic materials for cancer treatment. The freeze-drying process could maintain the color, flavor, and nutritional content of food by removing water from solid to gas phase directly under reduced pressure and low temperature. It is being harnessed to preserve active components and structures of human tissues as drug depots.Freeze-dried fruits and vegetables.Led by Prof...
ZJU doctors carry out living donor liver and kidney transplants in Uzbekistan
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2024-03-21
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In March, SAHZU transplantation team traveled 4000 km and demonstrated SAHZU surgical techniques in the Central Asian country of Uzbekistan.From March 11 to 15, Prof. WANG Weilin, President of the Second Affiliated Hospital Zhejiang University School of Medicine (SAHZU), and a SAHZU multidisciplinary team paid a visit to Uzbekistan for a five-day surgical operation demonstrations and academic exchange activities at the Republic Specialized Scientific-Practical Medical Center of Surgery Named Aft...
Dialogue@ZJU: With Prof. XU Haoxin, Dean of School of Basic Medical Sciences
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2024-03-13
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XU HaoxinDean, School of Basic Medical Sciences,Zhejiang UniversityQiushi Chair Professor of Zhejiang UniversityProfessor of Liangzhu LabVisiting Professor,Department of Biology,University of MichiganPresidential Early Career Award for Scientists and Engineers 2010Researcher of the New Cornerstone Investigator Program 2023President of the Zhejiang Society for Neuroscience Q1: What made you decide to come to Zhejiang University?XU: There are two things I considerfrequently:how to create some...
Teams from ZJU and MIT propose for the first time the concept of macroencapsulated bacteria
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2024-03-11
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In a recent collaboration, Assistant Prof. NAN Kewang, Prof. GU Zhen from the College of Pharmaceutical Science at Zhejiang University (ZJU), along with Prof. Robert S. Langer from the Massachusetts Institute of Technology (MIT), published a review paper Macroencapsulated bacteria for in vivo sensing and therapeutics in the peer-reviewed journal Matter. The article is one of the first in the field that defines the concept of “macroencapsulated bacteria”. Co-first authors are LYU...
“Trim” the heart and “strengthen” it!
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2024-03-07
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Myocardial hypertrophy, characterized by an increase in cardiac muscle mass, is an adaptive response to pathological stimuli such as hypertension and valve disease. While initially beneficial, sustained hypertrophy may lead to further disease progression and exacerbate heart failure, which is one of the most common and deadly medical conditions worldwide and remains incurable. Inhibition or reversal of cardiac hypertrophy and subsequent maladaptive myocardial remodeling is the main treatments fo...
Dialogue@ZJU: With Prof. WANG Jian'an, Academician of the Chinese Academy of Sciences
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2024-02-02
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[Editor’s Note: In this Dialogue@ZJU, we feature Prof. WANG Jian'an, Academician of the Chinese Academy of Sciences, Director of the National Key Laboratory of Vascular lmplantation Devices, Secretary of the Party Committee and Director of the Heart Center, Second Affiliated Hospital, Zhejiang University School of Medicine, and Vice Dean of Zhejiang University School of Medicine. From early inspirations rooted in family health challenges to pioneering the Hangzhou Solution for heart disease...