Iron-related cell death as a novel mechanism for heart diseases
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2019-02-01
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A research team led by WANG Fudi, a professor at the School of Public Health, Zhejiang University, discovers that ferroptosis, a programmed iron-dependent cell death, as a mechanism in murine models of doxorubicin (DOX)- and ischemia/reperfusion (I/R)-induced cardiomyopathy. Five effective approaches are explored to preventing cardiac injuries, including ferroptosis inhibitor Fer-1, iron chelatordexrazoxane (DXZ), mitochondria-targeted antioxidant MitoTEMPO, Hmox1 inhibitor zinc protoporphyrin I...
Analysis on liver cancer subpopulation identifies the key role of one microRNA
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2018-12-14
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The research team led by JI Junfang from the Life Sciences Institute, Zhejiang University, published an article entitled “miR-192-5p silencing by genetic aberrations is a key event in hepatocellular carcinomas with cancer stem cell features” in the December 7 issue of Cancer Research. It opens up a feasible and effective approach to targeting hepatocellular carcinomas with cancer stem cell features.Primary liver cancer is the second leading cause of cancer deaths worldwide and approximate...
ZJU researchers discover a new mechanism for gastric cancer metastases
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2018-12-01
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Recently, the research team headed by Prof. ZHOU Tianhua from the School of Medicine, Zhejiang University, published an article entitled “Long Non-coding RNA GMAN, Upregulated in Gastric Cancer Tissues, is Associated with Metastases in Patients and Promotes Translation of Ephrin A1 by Competitively Binding GMAN-AS” in the journal of Gastroenterology. They identified long non-coding RNAs (lncRNAs) that are upregulated in gastric cancer tissues from patients and did research into their func...
Researchers track down the culprit of deafness
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2018-09-10
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Recently, ZJU scientists “captured” a particular gene for hearing impairment: mtu1. Mtu1 deficiency results in the “power shortage” of our auditory organ. This research is published in the August 22 issue of Nucleic Acids Research.These findings are part and parcel of massive research into deafness treatment. The research team led by Prof. GUAN Minxin at ZJU’s Institute of Genetics is currently searching for more deafness-inducing genes among thousands of human genes.“Among 27.8 ...
New invention enables the blind to "see" the world
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2018-04-28
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“Glasses for the blind are changing constantly. The GPS has been incorporated into new versions and it is predicted that the state-of-the-art face-recognition software will tell the wearer who is standing in front of him,” said CHEN Zuobing, Director of the Rehabilitation Research & Development Center of the Industrial Technology Research Institute and Director of the Rehabilitation Medical Research Center of the School of Medicine, Zhejiang University.This pair of glasses is developed to ...
ZJU professor's depression research published in Nature
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2018-02-12
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According to the World Health Organization, depression is a common illness worldwide, with more than 300 million people affected. It can cause the affected person to suffer greatly and function poorly at work, at school and in the family. At its worst, depression can lead to suicide.Professor of Neurobiology HU Hailan has been doing impactful research into how emotional and social behaviors are encoded and regulated in the brain. On February 15, her team made a new breakthrough with tw...
ZJU doctors endeavor to fight Parkinson's disease
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/english/2018/0129/c65147a811173/page.psp
2018-01-29
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In 1817, English doctor James Parkinson published an essay describing the characteristic resting tremor, abnormal posture and gait, paralysis and diminished muscle strength, and the way that the disease progresses over time. Hence this disease was named Parkinson’s disease (PD) in honor of James Parkinson.Illustration of Parkinson's disease by William Richard Gowers, first published in A Manual of Diseases of the Nervous System (1886).“PD is a long-term degenerative disorder of the ce...